Journal of Thyroid Disorders & Therapy offers the most comprehensive and reliable information pertaining to the latest developments in the field. The Journal also believes in advancing new hypotheses and opinions by means of its high-quality Reviews, Perspectives, and Commentaries. Thus, the content published in the journal is original and comprehensive.

Thyroid eye disease is a condition in which the eye muscles, eyelids, tear glands and fatty tissues behind the eye become inflamed. This can cause the eyes and eyelids to become red, swollen and uncomfortable and the eyes can be pushed forward (‘staring’ or ‘bulging’ eyes). In some cases there is swelling and stiffness of the muscles that move the eyes so that they no longer move in line with each other; this can cause double vision. Rarely TED can cause reduced vision from pressure on the nerve at the back of the eye or ulcers forming on the front of the eyes if the eyelids cannot close completely.

Thyroid eye disease (TED) is a complex orbital inflammatory disease causing inflammation in the extraocular muscles, eyelids, lacrimal glands, and surrounding connective and adipose tissue, which could be sight-threatening and disfiguring. TED is also known as Graves’ ophthalmopathy, named after Robert J. Graves. Most patients with TED have biochemical evidence of hyperthyroidism. TED may also occur in patients who have hypothyroidism or euthyroidism. Uveitis is characterized by intraocular inflammation that might result from various systemic diseases. Patients of uveitis comorbidant with thyroid disease have been reported since 1915 and the association of thyroid disease with uveitis has recently received more attention. As the uvea is rich in blood vessels, immune system activation in one organ can result in hematogenous spread of inflammatory cells and cytokines into the eyes. Common pathophysiological mechanisms may be responsible for immune dysregulation in both thyroid disease and uveitis in certain individuals.

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Regards
Denise Williams
Editorial Manager     
Journal of Thyroid Disorders & Therapy
E-mail id: thyroiddisorders@longdomjournal.org