Background and purpose: Breast cancer is known as the most widely recognized and lethal disease among women. Various strategies including surgery, radiotherapy, and chemotherapy are applied to cure cancer. Chemotherapy, as a typical helpful strategy, brings about various physical and mental symptoms. Nausea and vomiting are amongst the most common widely recognized symptoms of chemotherapy. Regardless of advancement in anti-nausea and anti-vomiting medicines, nausea and vomiting are yet the most widely recognized reactions of chemotherapy. In one hand, alternative and complementary medicines are among basic and safety measurements. This study has been accomplished to compare the effect of sucking ice bits with plain water and ice bits containing of mint concentrate on nausea and vomiting during chemotherapy