IAPNE is educational and healthcare delivery model with a two-fold purpose of creating a built, yet flexible environment that promotes, fosters and extends inter professional collaborative practice for service agencies, while improving the Health- Related Quality Of Life (HRQOL) for underserved populations. This innovative practice is a system transforming model that achieves the World Health Organization???s (WHO) call for inter professional education and collaborative practice and the United States??? Healthy People 2020 objective of increase in self-reported better physical and mental health for the adult population. This practice model of IAPNE utilizes HRQOL initiatives that encompass physical, mental, emotional and social functioning.