Clinical & Medical Biochemistry is a quarterly peer reviewed, open access journal publishing the state of the art research in Clinical & Medical Biochemistry. The journal considers any material dealing primarily Clinical biochemistry, Immunology, Genetics, Biotechnology, Haematology, Microbiology, Computing and management, Clinical Chemistry, Medical biochemistry, biochemistry, Molecular Biology and Immunochemistry dealing with pathological conditions of human beings but not limited to the following fields.

The overall chemical composition of hair is 45 % carbon, 28 % oxygen, 15 % nitrogen, 7 % hydrogen and 5 % sulphur.

The hair shaft is basically made out of keratin. Hair keratin is hard, reduced and solid. This sinewy protein is bit by bit framed inside cells from the germinal layer. These fingernail skin cells are described by the presence of amorphous keratin while the cortical cells have a structure of fibres encompassed by a keratinic substance that is more extravagant in sulphur and contains amino acids. The keratin of these fibres frames a helix, with a distance between the turns of 0.51 nanometres and a structure kept up by hydrogen bonds. This protein assumes a critical job in the union and actual properties of hair.

Hair likewise contains water (12 to 15 %) and hints of mineral components (calcium, cadmium, chromium, copper, zinc, iron and silicon). These components can be brought to the base of the hair follicle by blood course and afterward add to building the hair shaft. Other than this commitment, the climate can, for instance through contamination, be the wellspring of specific components, for example, lead.

The hair additionally contains lipid segments (3% of its piece). They are created in the hair bulb from sterols, unsaturated fats and ceramides. Present basically in the intercellular concrete of the cortex and the fingernail skin, they give the hair a specific impermeability and guarantee the attachment of the hair fibre.

Different lipids come from the discharge of the sebaceous organ: sebum. Sebum is framed from develop sebaceous cells which have blasted open and it basically contains lipids (fatty substances, waxes, squalene, esterified cholesterol and free cholesterol). The most bountiful fatty substances go through fractional hydrolysis by the microorganisms that occupy the scalp, Propionibacterium acnes and Propionibacterium granulosum. This hydrolysis frees free unsaturated fats, di-and monoglycerides and glycerol. The unsaturated fats are portrayed via carbon chains, even and lopsided in number (from C11 to C19), with various unsaturated areas and branches. The waxes are esters of acids and long-chain alcohols. The waxes are apolar exacerbates which are processed by the vegetation and are minimal influenced by oxidation.

In the sebaceous organ, acetic acid derivation particles consolidate to shape mevalonic corrosive, an isoprenoid isomer and squalene, a direct hydrocarbon framed from 30 carbon molecules. The sterols are esterified by the unsaturated fats. The squalene/cholesterol proportion in the surface hydrolipidic film is a reflection of the organic exercises of the sebaceous organs and the epidermis. The lipid blend, which shapes this film on the outside of the skin greases up the hair and consequently saves the flexibility and sparkle of the hair. Being chemical ward, the sebum can be created in abundance and the hair gets oily and weighty. Then again, if too little is emitted, the hair gets dry, dull and harmed.

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Chris Benson
Managing editor
Clinical and Medical Biochemistry Journal
Twitter:@Clinical_Bioche
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Email: biochemistry@scholarlypub.com