Causes & Effects: Patients with Obesity & Thyroid Function Testing

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Journal of Thyroid Disorders & Therapy offers the most comprehensive and reliable information pertaining to the latest developments in the field. The Journal also believes in advancing new hypotheses and opinions by means of its high-quality Reviews, Perspectives, and Commentaries. Thus, the content published in the journal is original and comprehensive.

Thyroid function tests are a series of blood tests used to measure how well your thyroid gland is working. Available tests include the T3, T3RU, T4, and TSH. The thyroid produces two major hormones: triiodothyronine (T3) and thyroxine (T4). If your thyroid gland doesn’t produce enough of these hormones, you may experience symptoms such as weight gain, lack of energy, and depression. This condition is called hypothyroidism. If your thyroid gland produces too many hormones, you may experience weight loss, high levels of anxiety, tremors, and a sense of being on a high. This is called hyperthyroidism. Typically, a doctor who is concerned about your thyroid hormone levels will order broad screening tests, such as the T4 or the thyroid-stimulating hormone (TSH) test. If those results come back abnormal, your doctor will order further tests to pinpoint the reason for the problem.

A T3 resin uptake, also known as a T3RU, is a blood test that measures the binding capacity of a hormone called thyroxin-binding globulin (TBG). If your T3 level is elevated, your TBG binding capacity should be low. Abnormally low levels of TBG often indicate a problem with the kidneys or with the body not getting enough protein. Abnormally high levels of TBG suggest high levels of estrogen in the body. High estrogen levels may be caused by pregnancy, eating estrogen-rich foods, obesity, or hormone replacement therapy. A blood test measuring your hormone levels is the only accurate way to find out whether there's a problem. The test, called a thyroid function test, looks at levels of thyroid-stimulating hormone (TSH) and thyroxine (T4) in the blood. Doctors may refer to this as "free" T4 (FT4). A high level of TSH and a low level of T4 in the blood could mean you have an underactive thyroid.If your test results show raised TSH but normal T4, you may be at risk of developing an underactive thyroid in the future. The GP may recommend that you have a repeat blood test every so often to see whether you eventually develop an underactive thyroid.

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Regards
Denise Williams
Editorial Manager     
Journal of Thyroid Disorders & Therapy
E-mail id: thyroiddisorders@longdomjournal.org